Hair Dye Alert: PTDS Named Allergen of the Year 2025 – What You Need to Know

Introduction: Understanding the New Allergen of the Year in Hair Dyes

The American Contact Dermatitis Society (ACDS) has designated Toluene-2,5-diamine sulfate (PTDS), a chemical found in many permanent hair dyes, as the Allergen of the Year for 2025. This highlights a growing concern about allergic reactions to hair dye ingredients.

What is PTDS (Toluene-2,5-diamine sulfate)?

PTDS is an aromatic amine used in hair dyes, often as an alternative to paraphenylenediamine (PPD). While it can be a substitute for some, it can also trigger allergic reactions in sensitive individuals.

Who is at Risk for PTDS Allergy?

  • Hairdressers & Beauticians: Professionals with frequent exposure to hair dyes have a higher risk. Studies show PTDS positivity rates of 7.9% to 15.3% among hairdressers.
  • Individuals Using Permanent Hair Dyes: Anyone using hair dyes containing PTDS can develop an allergy.

Symptoms of PTDS Allergic Contact Dermatitis (ACD):

PTDS allergy symptoms are similar to PPD allergy, including:

  • Eczema on the hands
  • Rashes along the hairline
  • Irritation around the eyes (periorbital area)
  • Neck rashes

These symptoms occur in areas commonly exposed to hair dye.

Finding Safe Hair Dye Alternatives:

  • Read Ingredient Labels Carefully: “Natural” or “organic” hair dyes may still contain PTDS and PPD. Always review ingredients.
  • Patch Testing: Test a small amount of dye on your skin before full application.
  • PTDS as a PPD Alternative: If you’re allergic to PPD, testing for PTDS allergy may allow you to use PTDS-containing dyes.
  • Henna-Based Products: Individuals allergic to both PPD and PTDS should consider henna-based hair dyes.
  • Consult a Dermatologist: For accurate allergy testing and personalized recommendations.

Treatment for PTDS Allergy:

  • Avoid PTDS: The primary treatment is to eliminate exposure to PTDS by avoiding hair dyes containing it.
  • Medical Treatment: A doctor can prescribe topical steroids to help settle the reaction.

Key Takeaways:

  • PTDS is a significant allergen in hair dyes, especially for professionals.
  • Symptoms mimic PPD allergy, requiring careful diagnosis.
  • Ingredient awareness and patch testing are crucial for prevention.
  • Consult a dermatologist for allergy testing and safe hair dye alternatives.